New paper out in eLife: Mapping sequence structure in the human lateral entorhinal cortex

My new paper with Lorena Deuker and Christian Doeller is now out in eLife!

In this project, we investigated how subregions of the human entorhinal cortex map temporal relations for episodic memory. Using fMRI and virtual reality, we show that multi-voxel patterns change through learning to resemble the temporal structure of an event sequence. Participants navigated along a route through a virtual city and encountered events - finding objects in treasure chests. Before and after learning we showed participants images of these objects in random order in the MR scanner. We compared the similarity of activation paterns with which the entorhinal cortex responded to the objects. After learning, the similarity of these object representations correlated with the time elapsed between the object encounters along the route. Objects that were found close together in time became more similar relative to objects encountered with a long temporal gap. Our new findings also show that the strength of this entorhinal effect correlates with the way participants later order their recall of the events.

You can find the paper now in eLife.

JLS Bellmund, L Deuker, CF Doeller (2019). Mapping sequence structure in the human lateral entorhinal cortex. eLife 8, e45333.